Peptide purity is usually determined by reversed-phase HPLC, measuring the percentage of the target sequence against synthesis by-products like truncated or deletion chains. Purity ranges from Crude (50-70%)for non-sensitive screening to >98% for demanding quantitative studies and clinical applications.

>90% to 95%: The standard for general biological activity studies, enzyme assays, and non-quantitative in vitro experiments.

>95%: Required for quantitative analytical analysis, receptor binding studies, and general cell culture experiments.

>98% to 99%: Essential for in vivo studies, NMR, crystallography, or use as reference standards and regulatory-grade products. 

1. Pharmaceutical or Medical-Grade

• Purity: 98% to 99%+ purity with strictly controlled impurity thresholds. 

• Standards: Synthesized in FDA-registered or cGMP-compliant facilities. They undergo rigorous batch testing for heavy metals, sterility, and endotoxins, accompanied by a verified Certificate of Analysis (CoA). 

• Usage: Prescribed by licensed medical professionals and prepared by compounding pharmacies for clinical treatments (e.g., metabolic health, tissue repair).

2. Research-Grade

• Purity: Usually >90% to 98%, depending on the supplier.

• Standards: Labeled strictly for "Research Use Only" (RUO). While reputable suppliers provide mass spectrometry (MS) and HPLC data, these products are not regulated or manufactured for human consumption or injection.

• Usage: Utilized in laboratories, universities, and biotech companies for in vitro or animal studies. 

Kovera Labs

America's Trusted Peptide Lab

KOVERA LAB is the leading peptide lab and peptide analysis laboratory. Peptides tested with comprehensive peptide lab testing services including Purity + Net Content and Identity (LC-MS)

PepElite peptides are tested for:

Purity and major peak %

Net content (mg/vial) quantitation

Identity confirmation (LC-MS)

Clear pass/fail callouts 

 COAs for our peptides are listed below can be cross-checked on the Kovera Lab's website     Kovera Labs-Verify Our COAs Here! 

INFORMATION IS FOR EDUCATIONAL PURPOSES ONLY